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Research
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PubMed COVID-19 Clinical Care

38261 - 38270 of 58327 results found

Transmission and re-infection of Omicron variant XBB.1.5 in hamsters

Date
Friday, June 23, 2023 - 4:00 AM
Description
BACKGROUND: Like its predecessors in the XBB family, XBB.1.5 is highly immune evasive from therapeutic monoclonal antibodies and neutralizing antibodies generated by vaccination and/or infection. However, there is a lack of in vivo data on XBB.1.5 in

Optimality of Maximal-Effort Vaccination

Date
Friday, June 23, 2023 - 4:00 AM
Description
It is widely acknowledged that vaccinating at maximal effort in the face of an ongoing epidemic is the best strategy to minimise infections and deaths from the disease. Despite this, no one has proved that this is guaranteed to be true if the disease

Solvated interaction energy: from small-molecule to antibody drug design

Date
Friday, June 23, 2023 - 4:00 AM
Description
Scoring functions are ubiquitous in structure-based drug design as an aid to predicting binding modes and estimating binding affinities. Ideally, a scoring function should be broadly applicable, obviating the need to recalibrate and refit its

Endemic oscillations for SARS-CoV-2 Omicron-A SIRS model analysis

Date
Friday, June 23, 2023 - 4:00 AM
Description
The SIRS model with constant vaccination and immunity waning rates is well known to show a transition from a disease-free to an endemic equilibrium as the basic reproduction number r0 is raised above threshold. It is shown that this model maps to

The COVID-19 experience of orthodontists in Jordan

Date
Friday, June 23, 2023 - 4:00 AM
Description
CONCLUSIONS: Patients in active orthodontic treatment, during COVID-19, have been prioritized but at the expense of new and review patients. Respondents in Jordan felt COVID-19 would have ongoing effects on clinical care, professional practice, and