PubMed COVID-19 Clinical Care
22441 - 22450 of 58327 results found
Impact of COVID-19 on long-term lung function in lung transplant recipients: A single-center retrospective cohort study
Description
Available data are limited concerning long-term lung function (LF) evolution after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in lung transplant (LT) recipients. The aim of this study is to determine the effect of first
Association of Serum Complement C3 Levels with Severity and Mortality in COVID 19
Description
The severe acute respiratory distress syndrome-associated coronavirus-2 infection can activate innate and adaptive immune responses which may lead to harmful tissue damage, both locally and systemically. C3, a member of complement system of serum
Right Ventricle Thrombus in a Massive Pulmonary Embolism COVID-19 Patient
Description
The coronavirus disease 2019 (COVID-19) infection presents with a wild range of clinical manifestations. Increased inflammatory response and thrombotic risk have been described, being pulmonary embolism a potential cause of death in these patients
Heat shock protein 90 inhibition in the endothelium
Description
No abstract
The evolving role of data & safety monitoring boards for real-world clinical trials
Description
CONCLUSIONS: Clinical trials can benefit from incorporating real-world data sources, potentially increasing the generalizability of findings and overall trial scale and efficiency. The data, however, present a level of informatic complexity that
Symptom profiles and accuracy of clinical case definitions for COVID-19 in a community cohort: results from the Virus Watch study
Description
Background: Understanding symptomatology and accuracy of clinical case definitions for community COVID-19 cases is important for Test, Trace and Isolate (TTI) and future targeting of early antiviral treatment. Methods: Community cohort participants
Detection and characterization of novel luchacoviruses, genus Alphacoronavirus , shed in saliva and feces of meso-carnivores in the northeastern United States
Description
Small to mid-sized carnivores, or meso-carnivores, comprise a group of diverse mammals, many of which can adapt to anthropogenically disturbed environments. Wild meso-carnivores living in urban areas may get exposed to or spread pathogens to other
Complete substitution with modified nucleotides suppresses the early interferon response and increases the potency of self-amplifying RNA
Description
Self-amplifying RNA (saRNA) will revolutionize vaccines and in situ therapeutics by enabling protein expression for longer duration at lower doses. However, a major barrier to saRNA efficacy is the potent early interferon response triggered upon
Delayed inflammatory pulmonary syndrome: A distinct clinical entity in the spectrum of inflammatory syndromes in COVID-19 infection?
Description
CONCLUSION: This delayed respiratory worsening with elevated inflammatory markers and clinical response to immunomodulation appears to contrast the well described Multisystem Inflammatory Syndrome - Adults by the paucity of extrapulmonary organ
